Right fella's, on review, and after the knowledge that the Lyons building is 44 Hanover Street, for me, the road and location in question can only be one of two. Gradwell Street, or Seel Street.
Gradwell Street, running towards Wolstenholm Square, has the more pronounced bend in the road, but at the Hanover Street end, is nothing more wide than a one lane track.
Seel Street, although we think of it as straight, does have two bends in it. The bends arn't immediately noticable to the eye, but in the original photo,what I think has happened is that the lens on the camera has foreshortened the shot, and hence foreshortened the road making the kink in Seel Street look more pronounced.
So for me, the road in question is the bottom end of Seel street.
If you look at the map below, in blue is marked several 'works' including a foundry, a colour works, and a milling works, which would allow for the chimneys on the right side of the street, half way up just by the kink in the road.
On the opposite side of the road about the same distance up the street are more chimneys, of which, on the map are a Chemical laboratory, a distillery, and a cabinet works.
Last but not least. In the very foreground of the original photo, there is a waggon side on, parked on a corner.
If you look at the original map, there is very few streets off that side of Hanover Street, and only one that almost ajoins a street oposite. That is the one facing Seel street. (marked in red on the map)
So I reckon the original photographer is somewhere in the Paradise Street area, looking over the rooves along Seel Street from the bottom, towards the cathedral.
And oh yes, 44 Hanover is between Gradwell Street and Seel Street, in the 1900 Gore's directory that I have it's listed as Tyrer's Buildings.
That would put Lyon's building at number 44, on the corner of Hanover Street and Gradwell Street.
