My only concern with the idea of a female Doctor is visions of a
Janeway-like character, who the Voyager producers felt had to always be the best at everything as they didn't want to have male characters be seen to talk down to her... That might work in
Who actually, where usually the Doctor is genuinely the best, most knowledgable person in the group.
Sod it, I'm in. As long as it's not literally Janeway.
Spoiler
I don't think Comic Book Guy could handle it...
But what character archetype would the (presumably male) companion be? Unless we're bringing Bill back for more 'young companion pines after the sexy older Doctor' scenarios.