Depends entirely on the game for me - think we need to move away from the idea of a fixed 11 and start thinking about tailoring our selections to the actual games (we've not had the luxury of doing that in quite some time).
I'm hesitant about him back there as the deepest player - I know some will point to a handful of games last season but he's played some 120+ games for us now and I've yet to see him convince back there over any extended period. I'm not sure he (at the moment) has the discipline or stamina for it. Particularly in frustrating home games where the opposition sit deep - our problem in those games is principally inability to move and circulate the ball quickly/effectively enough and getting caught on the counter. For all his qualities Can is probably our most sluggish midfielder on the ball, he wants too many touches and too much time on it. He also loves to maraud forward, and whilst I know people were calling for our deepest midfielder to dribble more when they were digging out Henderson earlier in the season, it'd be bordering on suicidal in our already vulnerable system, particularly given his propensity to give the ball away when he does it. He has a good switch of play on him, and a good passing range from deep, but he wants far too much time and space on the ball to be able to do it really. Playmaker, he is not.
I think in the bigger games where teams come to play and it's a bit more frenetic he could be a good option there - likewise in those tough away games against cloggers who want to try and bully us (to be clear, I'm not suggesting that that is Can's level - just that his aggression means he quite often shines in those circumstances).
It's tough because I'm not sure he's a natural fit at 6 or 8 in the way that we currently play it - he's probably not quick enough on the ball to be elite at 8 for us (and I suspect if we do sign a top CM in the summer, it will be in that position, and we may see Coutinho back there more often next year if we bring in another top wide player) so 6 is probably his best route into the team, but again, I don't think it necessarily suits his skillset. I think his best position would be in a flat midfield 2 where the combination of being pretty good at attacking and pretty good defensively is what you need. As it stands, I'm not sure he's consistent enough at either side of the game to be more of a specialist in either role.