One of the perils of having South American players I suppose, they seem to play a ridiculous amount of international football. I think we'll miss Suarez and Lucas more when the WC qualifiers start, usually the amount of travelling means players are in no fit state to play at the weekend when they have just travelled back from South America.
We can probably absorb the after-effects of the Copa America, especially if we aren't competing in Europe. Even players who play in the latter stages should be able to have 3 weeks off and retain some match fitness.