Every game is huge. If only the players realised that.
They're just people, with the same unavoidable problems (injuries, fatigue, issues in personal relationships, etc.) that effect you and me. No one wins them all over any given season. We just need to dial up our consistency a couple of notches.
It's about accumulated, marginal improvements, not one giant and magical realization that every game matters, they know that. Klopp is teaching them to working harder on the basic stuff than the opposition and that is better than trying to simply out-skill them.