If Henderson and Coutinho are fit to start, I'd be going with:
Firmino
Coutinho Origi
Lallana Wijnaldum
Henderson
Milner Klavan Lovren Clyne
Mignolet
Subs: Karius, Moreno, Gomez, Lucas, Can, Ojo, Sturridge
.
Firmino and Lallana back in their best positions. Harsh on Karius after last night's performance but Jurgen has made Mignolet our number one again. Can and Sturridge on the bench and Origi providing pace and running in behind in the absence of Mane. Concerned about our centre backs though! Matip is a big loss.
Agree, think/hope this is the team. Unless there's a surprise Matip
I'd have a slightly different bench. Only one of Gomez and Lucas, replaced by Stewart. I'd probably have Lucas on the bus as #8 sub, since he's already played 180 minutes this week. An early injury to Lovren or Klavan would leave us in big trouble for the end of the second half. Would prefer Stewart to replace Henderson than Can or Lucas too, and we have to prepare for him maybe needing a substitution. It's a toss up for me between Woodburn/Ejaria/Ojo for last spot. Probably agree Ojo, as he's most experienced and natural fit for the right of the front three.
As you say, this puts everyone bar Origi in their best positions. And Origi had his best non-9 performance against Stoke recently, in terms of contributing to our build up and pressing, so hopefully we see a similar performance (with a little more goal threat)