Echo
The club remain hopeful, however, that the injury isn't too serious and Lovren is able to return sooner rather than later as the Reds' Premier League title charge enters a crucial period.
Gomez was enjoying a fine season for the Premier League leaders before he suffered a fractured leg in the 3-1 win over Burnley last month.
The England international has missed the last eight games and is still someway from a return with a definitive comeback yet to be pencilled in.
Matip, who injured his collarbone in the 1-0 win over Napoli on December 11, is expected back before Gomez but this weekend's game will come too soon for the former Schalke star
The 27-year-old will be assessed next week ahead of the home game against Roy Hodgson's Crystal Palace.