Switching flanks isn't normally an issue and I'm sure many can do it. Many teams/managers decide to play a lefty on the right or vice versa, as cover or as a tactic or somesuch, but I'm just of the opinion that it shouldn't happen, IF we can help it, in a "high profile" game, because what happens in those split-seconds when instinct takes over, or a split-second quick decision needs to be made? The moments that determine such games?
You get a shot on goal, but instinctively decide to roll it over to your left (or doubt about your ability creeps in) in the heat of the moment..... and the chance is gone, and you're in the 95th minute, at 1-1 or 2-1 down and it's a crucial game in the race or a knockout tie.
You get a pass and under pressure from a predator of a striker, you decide to control it with your left, instead of your right- an instinctive decision... and blam!- you're dispossesed and flat on your arse as he goes onto score.
It will work in bread and butter games and that's where I would rather see it, but very risky in the big matches. And you become the target for those top attackers during that game- to add to the pressure. The goal is not just to beat you- everyone knows you're a top player, but to put you under pressure so you can be forced to make a pivotal instinctive decision and hopefully, a "mistake", because that's not your usual position.