It will be interesting how they fold in the backstory, but I'd be willing to bet that Dan Aykroyd will have some part to play in that - said it in an earlier post, they'll more than likely go use a framework of Bridesmaid-like proportions. I find it ironic that they've released a picture of the cast posing in front of Ecto-1. A film that will be a McCarthy/Wiig vehicle - much like Stiller/Wilson, even Murray/Aykroyd back in the day.
I've always felt that the only way a truly good Ghostbusters 're-boot' would either be a CGI Disneyfied carbon-copy like Yellow Submarine, or a TV Sci-Fi (But not Syfy) series.
This will be in Poundstretcher on the DVD shelf in three years time, and if it isn't, justice ain't justice.