Salah will be an interesting one, he basically has very reduced defensive responsibilities currently, I can’t see that remaining with Slot coming in.
Salah will definitely be a very very complex dilemna to solve. He has so much to offer offensively and nearly nothing defensively.
Slot, with wanting his team to defend from the front, will need him to perform defensive duties. But I think he can play the role of that "holding AM" during an attack phase, and hold it for the wingers to get into position.
By modifying his game to have more "holding" character, he could effectively be either attacking (which he is world class good at) and charge himself at the goal, or hold the ball and shield it for the team to get forward.
But its sure that his game has to change and he will probably become more withdrawn and become less potent in banging in goals. So no more 20 goals or 25 goals. More like 12-15 goals, 12-15 assists and a couple of penalties here and there.