Author Topic: Paralysed man walks again.  (Read 1768 times)

Offline Red Beret

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Paralysed man walks again.
« on: October 21, 2014, 09:07:41 am »
http://www.theguardian.com/science/2014/oct/21/paralysed-darek-fidyka-pioneering-surgery

Quote

A man who was completely paralysed from the waist down can walk again after a British-funded surgical breakthrough which offers hope to millions of people who are disabled by spinal cord injuries.

Polish surgeons used nerve-supporting cells from the nose of Darek Fidyka, a Bulgarian man who was injured four years ago, to provide pathways along which the broken tissue was able to grow.

The 38-year-old, who is believed to be the first person in the world to recover from complete severing of the spinal nerves, can now walk with a frame and has been able to resume an independent life, even to the extent of driving a car, while sensation has returned to his lower limbs.

Professor Geoffrey Raisman, whose team at University College London’s institute of neurology discovered the technique, said: “We believe that this procedure is the breakthrough which, as it is further developed, will result in a historic change in the currently hopeless outlook for people disabled by spinal cord injury.”

The surgery was performed by a Polish team led by one of the world’s top spinal repair experts, Dr Pawel Tabakow, from Wroclaw Medical University, and involved transplanting olfactory ensheathing cells (OECs) from the nose to the spinal cord.

OECs assist the repair of damaged nerves that transmit smell messages by opening up pathways for them to the olfactory bulbs in the forebrain.

Relocated to the spinal cord, they appear to enable the ends of severed nerve fibres to grow and join together – something that was previously thought to be impossible.

While some patients with partial spinal injury have made remarkable recoveries, a complete break is generally assumed to be unrepairable.

The research, funded by the Nicholls Spinal Injury Foundation (NSIF) and the UK Stem Cell Foundation, features in a BBC Panorama programme on Tuesday night.

Raisman, who hopes to see at least three more patients treated in Poland over the next three to five years if the funding can be raised, said: “The patient is now able to move around the hips and on the left side he’s experienced considerable recovery of the leg muscles.

“He can get around with a walker and he’s been able to resume much of his original life, including driving a car. He’s not dancing, but he’s absolutely delighted,” said Raisman.

The NSIF’s founder, David Nicholls, whose son Daniel was paralysed in 2003, said information relating to the breakthrough will be made available to other researchers around the world to help cure paralysis.

He said: “Paralysis is something that most of us don’t know very much about, because we are not affected by it. One of the most devastating moments a parent will ever experience is the sight of their son or daughter lying motionless in bed and facing the reality that they may never walk again.

“The scientific information relating to this significant advancement will be made available to other researchers around the world so that together we can fight to finally find a cure for this condition which robs people of their lives.”

Raisman said he had never believed the “observed wisdom” that the central nervous system cannot regenerate damaged connections.

He added: “Nerve fibres are trying to regenerate all the time. But there are two problems – crash barriers, which are scars, and a great big hole in the road.

“In order for the nerve fibres to express that ability they’ve always had to repair themselves, first the scar has to be opened up, and then you have to provide a channel that will lead them where they need to go.”

He stressed that what had been achieved was a leap forward beyond promoting “plasticity” – the rewiring of remaining connections.

The professor added: “The number of patients who are completely paralysed is enormous. There are millions of them in the world.

“If we can convince the global neurosurgeon community that this works then it will develop very rapidly indeed.”
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Offline wampa1

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Re: Paralysed man walks again.
« Reply #1 on: October 21, 2014, 12:14:18 pm »
Somewhere, IDS is rubbing his hands glee

Offline Bird Bird Bird The Bird Is The Word

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Re: Paralysed man walks again.
« Reply #2 on: October 21, 2014, 01:28:14 pm »
Incredible, a genuine recovery from a complete break.

Offline plura

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Re: Paralysed man walks again.
« Reply #3 on: October 21, 2014, 04:54:09 pm »
Incredible, a genuine recovery from a complete break.

Did I misread the article? It says here: "While some patients with partial spinal injury have made remarkable recoveries, a complete break is generally assumed to be unrepairable".

Offline RedGlen

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Re: Paralysed man walks again.
« Reply #4 on: October 21, 2014, 04:58:28 pm »
Did I misread the article? It says here: "While some patients with partial spinal injury have made remarkable recoveries, a complete break is generally assumed to be unrepairable".

I think that's what the article is on about, allegedly this is the first time they have been able to restore function after a complete break in an individual. If true it may well open up new fields of medical research and treatment for individuals suffering from paralysis.
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Offline gazzam1963

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Re: Paralysed man walks again.
« Reply #5 on: October 21, 2014, 10:17:21 pm »
On panorama about it at 10-30 pm tonight

Offline redbyrdz

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Re: Paralysed man walks again.
« Reply #6 on: October 21, 2014, 10:18:18 pm »
Did I misread the article? It says here: "While some patients with partial spinal injury have made remarkable recoveries, a complete break is generally assumed to be unrepairable".


There's a bit more in the bbc article linked below.

Basically, this man had a mostly severed spinal chord after a knife attack. There was a bit of scar tissue on the right side, and a gap of about 8mm on the left side. He had no control over his lower body, even after two years of extensive physio. After the treatment, the gap has closed and he can now walk, with better recovery on the left side.

http://www.bbc.co.uk/news/health-29645760
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Offline WavertreeRed

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Re: Paralysed man walks again.
« Reply #7 on: October 22, 2014, 02:47:02 pm »
Quote
Raisman, who hopes to see at least three more patients treated in Poland over the next three to five years if the funding can be raised,

You would think at least one of the Billionaires in the world would find it in their hearts to finance ground breaking research like this. The amount of improvement to someones life this could make is immeasurable.

Or they might just buy another yacht/football team :butt
Will you please kindly refrain from all this rational common sense bollocks.

Someone has said something on a social networking site, so it must be true.

Offline Red Beret

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Re: Paralysed man walks again.
« Reply #8 on: October 22, 2014, 07:04:07 pm »
You would think at least one of the Billionaires in the world would find it in their hearts to finance ground breaking research like this. The amount of improvement to someones life this could make is immeasurable.

Or they might just buy another yacht/football team :butt

I'm sure if Christopher Reeve was still alive they would have.
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Re: Paralysed man walks again.
« Reply #9 on: October 22, 2014, 08:01:28 pm »
Sign him up Brendan, he can go in goal or defence.
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Offline sirjames

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Re: Paralysed man walks again.
« Reply #10 on: October 23, 2014, 10:12:30 am »
Strange coincidence - I have said David Nicholls form that article old phone number i think. I have litterally had 30/40 calls and texts some from new york congratulating me ... I am not David Nicholls.

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Re: Paralysed man walks again.
« Reply #11 on: October 23, 2014, 11:39:56 am »
those who assess fitness for disability benefits dont know whether to cheer or fear the improvements made in modern medicine.