It's sort've like agnostic.
Let's say you have a set of square building foundations
You then have 4 building designs which can fit on top of those foundations but their facade structure is layout "agnostic" (this is where my word is required)
You then have 4 tins of paint all different colours, these would be structurally "agnostic" (this is where my word is required) as they are not affected by the house structure.