The likes of Alisson, Van Dijk, Fabinho, Henderson, Jota, Salah and Mane should be nowhere near this one. I would add Trent, Robertson and Matip to that list as well normally but we would want to keep their fitness ticking over so maybe they get some minutes off the bench.
There are plenty of players who could do with the minutes such as Origi, Gordon, Minamino, Phillips, Oxlade-Chamberlain, Konate, Gomez etc.