I think Shakhtar have a good chance. They play very aggressive and could be able to interrupt Barcas build up play with their engagement. I smell a sensation right there.
Inter should get past Schalke, but it won't be easy. Rangnick is a top coach and he'll do everything he can to get through and Inter will be missing Lucio in the first of two games, which makes their defense even worse.
Real to beat Tottenham, no way Redknapp will beat Mourinho over two legs. Just impossible.
And last but not least: United - Chelsea. Fantastic pairing, Chelsea to get through.